yneA [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]

inhibits cell division during SOS response

locus: BSU17860

pI: 4.00

mw: 11.00 kDa

function: inhibits cell division during SOS response

product: cell division control protein

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes]

[SW|Categories] containing this gene/protein

• [SW|cell division]

This gene is a member of the following [SW|regulons]

• [SW|LexA regulon]

Gene

Coordinates on the chromosome (coding sequence): 1,918,406 -> 1,918,723

Phenotypes of a mutant

• increased sensitivity to DNA-damaging agents [Pubmed|23728628]

The protein

Protein family

• yneA family (according to Swiss-Prot)

[SW|Domains]

• contains a N-acetylglucosamine-polymer-binding [SW|LysM domain] (aa 38-89) [Pubmed|20400548,18430080]

[SW|Localization]

• secreted to the medium (signal peptide) [Pubmed|20400548]

Expression and Regulation

Operon

• ''[protein|search|yneA]-[protein|search|yneB]-[protein|search|ynzC]'' [Pubmed|12581363]

Regulation

• induced by DNA damage ([protein|search|LexA]) [Pubmed|12581363]

Regulatory mechanism

• [protein|search|LexA]: transcription repression [Pubmed|12581363]

Additional information

• YneA is rapidly degraded by extracellular proteases [PubMed|20400548]

References

Reviews

• 22933559,18430080

Original publications

• 12581363,20400548,16267290,23728628