SubtiBank SubtiBank
yneA
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yneA

inhibits cell division during SOS response
Locus
BSU_17860
Isoelectric point
4.61
Molecular weight
11.75 kDa
Protein length
105 aa Sequence Blast
Gene length
318 bp Sequence Blast
Function
inhibits cell division during SOS response
Product
checkpoint enforcement protein
Essential
no
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,918,406 1,918,723

Phenotypes of a mutant

  • increased sensitivity to DNA-damaging agents PubMed
  • inactivation allows growth of a whiA parB double mutant PubMed
  • The protein

    Protein family

  • YneA family (single member, according to UniProt)
  • Domains

  • contains a N-acetylglucosamine-polymer-binding LysM domain (aa 38-89) PubMed
  • Localization

  • secreted to the medium (signal peptide) PubMed
  • Expression and Regulation

    Operons

    Description

    Regulatory mechanism

  • LexA: repression, PubMed, in LexA regulon
  • Regulation

  • induced by DNA damage (LexA) PubMed
  • Additional information

  • YneA is rapidly degraded by extracellular proteases (CtpA) PubMed
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    Biological materials

    Mutant

  • MGNA-B388 (yneA::erm), available at the NBRP B. subtilis, Japan
  • BKE17860 (yneA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATAACCTCCAACAGGAATG, downstream forward: _UP4_AGATAGAGAGGAAAGAGAGA
  • BKK17860 (yneA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATAACCTCCAACAGGAATG, downstream forward: _UP4_AGATAGAGAGGAAAGAGAGA
  • References

    Reviews

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    Original publications

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