mnaA [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

UDP-N-acetylglucosamine 2-epimerase

locus: BSU35660

pI: 5.47

mw: 42.00 kDa

function: biosynthesis of teichoic acid

product: UDP-N-acetylglucosamine 2-epimerase

essential: yes

ec: 5.1.3.14

synonyms: yvyH

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.4|Biosynthesis of teichoic acid]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.3|Biosynthesis of teichoic acid]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[SW|Categories] containing this gene/protein

• [SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence): 3,664,241 -> 3,665,383

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine (according to Swiss-Prot)

Protein family

• UDP-N-acetylglucosamine 2-epimerase family (according to Swiss-Prot)

Structure

• [PDB|1O6C] [Pubmed|16021622]

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

References

Reviews

• 24024634

Original publications

• 12107153,16021622,24470206