ftsL [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

cell-division protein (septum formation), controls together with EzrA dynamics of the FtsZ ring

Locus: BSU15150

Isoelectric point: 10.00

Molecular weight: 12.00 kDa

Function: septum formation

Product: cell-division protein

Essential: yes

Synonyms: ylxB, yllD

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Cell envelope and cell division → Cell division → Other genes
• Groups of genes → Essential genes
• Groups of genes → Membrane proteins

Categories containing this gene/protein

• cell division, essential genes, membrane proteins

Gene

Coordinates on the chromosome (coding sequence): 1,581,597 -> 1,581,950

Phenotypes of a mutant

• essential PubMed

The protein

Protein family

• ftsL family (according to Swiss-Prot)

Effectors of protein activity

• degraded by RasP, stabilized against RasP cleavage by DivIC PubMed

Localization

• cell membrane (according to Swiss-Prot)

Interactions

• RasP-FtsL, DivIC-FtsL PubMed
• PbpB-DivIB-(FtsL-DivIC)2 PubMed, as part of the divisome
• WalK-FtsL PubMed

Expression and Regulation

Operon

• mraZ-mraW-ftsL-pbpB PubMed

Regulation

• constitutively expressed PubMed

Additional information

• FtsL is degraded by RasP PubMed

Biological materials

Mutant

• MGNA-B127 (ylyB::erm), available at the NBRP B. subtilis, Japan

FLAG-tag construct

• GP2004 ftsL-3xFLAG ermC (based on pGP1087), available in Jörg Stülke's lab

References

Reviews

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Original Publications

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