cell-division protein (septum formation), controls together with EzrA dynamics of the FtsZ ring
function
septum formation
product
cell-division protein
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|cell division], [SW|essential genes], [SW|membrane proteins]Gene
Coordinates on the chromosome (coding sequence)
1,581,597 -> 1,581,950
Phenotypes of a mutant
essential [Pubmed|12682299]The protein
Protein family
ftsL family (according to Swiss-Prot)Effectors of protein activity
degraded by [protein|search|RasP], stabilized against [protein|search|RasP] cleavage by [SW|DivIC] [Pubmed|20644139][SW|Localization]
cell membrane (according to Swiss-Prot)[SW|Interactions]
[protein|search|RasP]-[protein|search|FtsL], [SW|DivIC]-[protein|search|FtsL] [Pubmed|10844672][protein|search|PbpB]-[SW|DivIB]-([protein|search|FtsL]-[SW|DivIC])2 [Pubmed|20870765], as part of the [SW|divisome][protein|search|WalK]-[protein|search|FtsL] [Pubmed|21219466]Expression and Regulation
Operon
''[protein|search|mraZ]-[protein|search|mraW]-[protein|search|ftsL]-[protein|search|pbpB]'' [Pubmed|8636036,8244929]Regulation
constitutively expressed [Pubmed|23701187]Additional information
FtsL is degraded by [protein|search|RasP] [PubMed|17020588]Biological materials
FLAG-tag construct
GP2004 ''ftsL-3xFLAG ermC'' (based on [SW|pGP1087]), available in [SW|Jörg Stülke]'s labReferences
Reviews
Original Publications
9720875,10792716,16936019,16549676,17020588,8636036,10986263,11994149,10844672,19429628,20644139,21219466,23701187,20870765