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mdtR [2018-03-02 17:09:58]
transcription repressor of the multidrug-resistance [gene|795D70E8A4D750140D6B1AA4BFEBD25C2A389C85|mdtR]-[gene|search|mdtP ]operon
function
regulation of the multidrug-resistance [gene|795D70E8A4D750140D6B1AA4BFEBD25C2A389C85|mdtR]-[gene|search|mdtP ]operon
product
transcription repressor ([SW|MarR family])
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]Gene
Coordinates
3,374,492 → 3,374,959
The protein
Expression and Regulation
Operons
genes
[gene|795D70E8A4D750140D6B1AA4BFEBD25C2A389C85|mdtR]-[gene|45C61C1584A851676F15A2249F3F1092863C5AA5|mdtP]
description
[Pubmed|19286808]
regulatory mechanism
[protein|795D70E8A4D750140D6B1AA4BFEBD25C2A389C85|MdtR]: repression, [Pubmed|19286808], in [regulon|795D70E8A4D750140D6B1AA4BFEBD25C2A389C85|MdtR regulon]view in new tabBiological materials
Mutant
MGNA-B595 (yusO::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1594 NBRP B. subtilis, Japan]GP1115 (spc), available in [SW|Stülke] labBKE32870 (Δ[gene|795D70E8A4D750140D6B1AA4BFEBD25C2A389C85|mdtR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE32870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTCATTTCCCCTCTGT, downstream forward: _UP4_CAAAACATGAAAAGAGGAAABKK32870 (Δ[gene|795D70E8A4D750140D6B1AA4BFEBD25C2A389C85|mdtR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK32870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTCATTTCCCCTCTGT, downstream forward: _UP4_CAAAACATGAAAAGAGGAAAReferences