SubtiBank SubtiBank
mdtR
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mdtR

transcription repressor of the multidrug-resistance mdtR-mdtP operon
Locus
BSU_32870
Isoelectric point
6.38
Molecular weight
17.26 kDa
Protein length
155 aa Sequence Blast
Gene length
468 bp Sequence Blast
Function
regulation of the multidrug-resistance mdtR-mdtP operon
Product
transcription repressor (MarR family)
Essential
no
Synonyms
yusO
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Regulation of gene expression → Transcription factors and their control → Transcription factors/ other
  • Lifestyles → Coping with stress → Resistance against toxins/ antibiotics

    • Gene

    Coordinates
    3,374,492 3,374,959

    The protein

    Protein family

  • MarR family

    • Domains

  • HTH marR-type domain (aa 4-140) (according to UniProt)

    • Structure

  • 1S3J

    • Expression and Regulation

    Operons

    Genes
    mdtR-mdtP
    Description
    PubMed

    Regulatory mechanism

  • MdtR: repression, PubMed, in MdtR regulon
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    Biological materials

    Mutant

  • MGNA-B595 (yusO::erm), available at the NBRP B. subtilis, Japan
  • GP1115 (spc), available in Jörg Stülke's lab
  • BKE32870 (mdtR::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTCATTTCCCCTCTGT, downstream forward: _UP4_CAAAACATGAAAAGAGGAAA
  • BKK32870 (mdtR::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTCATTTCCCCTCTGT, downstream forward: _UP4_CAAAACATGAAAAGAGGAAA

    • References

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