rpsD [2018-05-30 17:48:01]

ribosomal protein

Locus: BSU29660

Isoelectric point: 10.24

Molecular weight: 22.69 kDa

Protein length: 200 aa

Gene length: 600 bp

Function: translation

Product: ribosomal protein S4 (BS4)

Essential: yes

Synonyms

Genomic Context

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Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Translation → Ribosomal proteins
• Groups of genes → Essential genes
• Groups of genes → Universally conserved proteins

Gene

Coordinates: 3,035,730 → 3,036,332

Phenotypes of a mutant

• essential PubMed

The protein

Protein family

• ribosomal protein S4P family (according to Swiss-Prot)

Structure

• 1C06 (Geobacillus stearothermophilus)
• 3J9W (the ribosome) PubMed

Expression and Regulation

Operons

• Genes: rpsD
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Regulatory mechanism

  • stringent response: negative regulation, in stringent response
  • RpsD: autorepression, PubMed, in RpsD regulon

  Regulation

  • autorepression of rpsD expression upon binding of excess RpsD to a RNA switch in the untranslated region of the rpsD mRNA PubMed

  Additional information

  • term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of rpsD PubMed
  • the RNA switch RNA is degraded by RNase Y PubMed

References

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