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araE [Mon Aug 31 2015 13:56:52 GMT+0200 (CEST)]
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araE [Mon Aug 31 2015 13:56:52 GMT+0200 (CEST)]

L-arabinose permease
locus
BSU33960
pI
9.26
mw
50.00 kDa
function
uptake of arabinose, galactose and xylose
product
L-arabinose permease
essential
no
synonyms
yvbR

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.3|Carbohydrate transporter]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.5|Utilization of xylan/ xylose]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.6|Utilization of arabinan/ arabinose/ arabitol]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • syns
    yvbR

    [SW|Categories] containing this gene/protein

  • [SW|transporters/ other], [SW|utilization of specific carbon sources], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|AraR regulon], [SW|CcpA regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • transports arabinose, and also xylose and galactose [Pubmed|9620981]
  • Paralogous protein(s)

  • [protein|search|CsbC], [protein|search|IolT], [protein|search|YfiG], [protein|search|YncC], [protein|search|YwtG]
  • Structure

  • [PDB|4JA4] (the xylose transporter XylE from ''E. coli'', 39% identity, 68% similarity) [Pubmed|23624861]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''araE'' [Pubmed|9401028]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|9401028]
  • Regulation

  • repressed by glucose ([protein|search|CcpA]) [Pubmed|12949161]
  • induced by arabinose ([protein|search|AraR]) [Pubmed|9401028,9620981,10417639]
  • Regulatory mechanism

  • [protein|search|CcpA]: transcription repression [Pubmed|12949161]
  • [protein|search|AraR]: transcription repression [Pubmed|9401028,9620981,10417639]
  • References

  • 9401028,9620981,23624861,10417639,9620981,12949161