function
uptake of arabinose, galactose and xylose
product
L-arabinose permease
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.3|Carbohydrate transporter][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.5|Utilization of xylan/ xylose][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.6|Utilization of arabinan/ arabinose/ arabitol][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|transporters/ other], [SW|utilization of specific carbon sources], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|AraR regulon], [SW|CcpA regulon]The protein
Catalyzed reaction/ biological activity
transports arabinose, and also xylose and galactose [Pubmed|9620981]Paralogous protein(s)
[protein|search|CsbC], [protein|search|IolT], [protein|search|YfiG], [protein|search|YncC], [protein|search|YwtG]Structure
[PDB|4JA4] (the xylose transporter XylE from ''E. coli'', 39% identity, 68% similarity) [Pubmed|23624861][SW|Localization]
cell membrane (according to Swiss-Prot)Expression and Regulation
Operon
''araE'' [Pubmed|9401028][SW|Sigma factor]
[protein|search|SigA] [Pubmed|9401028]Regulation
repressed by glucose ([protein|search|CcpA]) [Pubmed|12949161]induced by arabinose ([protein|search|AraR]) [Pubmed|9401028,9620981,10417639]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|12949161][protein|search|AraR]: transcription repression [Pubmed|9401028,9620981,10417639]References
9401028,9620981,23624861,10417639,9620981,12949161