opuCD [2019-09-25 09:13:16]

glycine betaine/carnitine/choline/arsenobetaine/arsenocholine ABC transporter

Locus: BSU_33800

Isoelectric point: 10.15

Molecular weight: 24.40 kDa

Protein length: 229 aa

Gene length: 690 bp

Function: compatible solute transport

Product: glycine betaine/carnitine/choline/arsenobetaine/arsenocholine ABC transporter

Essential: no

Synonyms: yvbB

Genomic Context

Loading

Categories containing this gene/protein

• Cellular processes → Transporters → ABC transporters → Importers → Uptake of compatible solutes for osmoprotection
• Lifestyles → Coping with stress → Coping with hyper-osmotic stress
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,467,546 3,468,235

The protein

Catalyzed reaction/ biological activity

• uptake of glycine betaine, arsenocholine and arsenobetaine PubMed

Protein family

• Binding-protein-dependent transport system permease family (according to UniProt)
• CysTW subfamily (according to UniProt)

Paralogous protein(s)

• OpuBD

Localization

• cell membrane PubMed

Expression and Regulation

Operons

• Genes: opuCA-opuCB-opuCC-opuCD
  Description: PubMed

  Regulatory mechanism

  • OpcR: repression, (sterical interference with RNA polymerase access) PubMed, in OpcR regulon
  • RemA: activation, PubMed, in RemA regulon
  • YlxR: regulation, PubMed, in YlxR regulon

  Regulation

  • induced by salt stress PubMed
  • induced in the absence of YlxR PubMed

Biological materials

Mutant

• BKE33800 (opuCD::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTCCATATGATCCACCTCTT, downstream forward: _UP4_TAAATACAACAGAGGTGGTT
• BKK33800 (opuCD::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TTCCATATGATCCACCTCTT, downstream forward: _UP4_TAAATACAACAGAGGTGGTT

References

Reviews

Loading

Original publications

Loading