gmuC [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

glucomannan-specific phosphotransferase system, EIIC component of the PTS

Locus: BSU05830

Isoelectric point: 9.80

Molecular weight: 48.00 kDa

Function: glucomannan uptake and phosphorylation

Product: glucomannan-specific phosphotransferase system,
EIIC component

Essential: no

Synonyms: ydhO

Genomic Context

Loading

Categories containing this gene/protein

• Cellular processes → Transporters → Phosphotransferase system → Sugar specific PTS proteins
• Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of glucomannan
• Groups of genes → Efp-dependent proteins

Categories containing this gene/protein

• phosphotransferase systems, utilization of specific carbon sources

This gene is a member of the following regulons

• AbrB regulon, CcpA regulon, GmuR regulon, Efp-dependent proteins

Gene

Coordinates on the chromosome (coding sequence): 627,284 -> 628,612

The protein

Protein family

• PTS permease, lactose permease (Lac) family PubMed

Paralogous protein(s)

• LicC, YwbA

Structure

• 3QNQ (EIIC component of diacetylchitobiose specific PTS from Bacillus cereus; 41% identity, 80% similarity) PubMed

Interactions

• GmuB-GmuC

Expression and Regulation

Operon

• gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG PubMed

Sigma factor

• SigA PubMed

Regulation

• induced by conjac glucomannan (requires GmuG) (GmuR) PubMed
• induced by cellobiose (GmuR) PubMed
• subject to carbon catabolite repression (CcpA) PubMed

Regulatory mechanism

• GmuR: transcription repression PubMed
• CcpA: transcription repression PubMed
• AbrB: transcription activation PubMed

Additional information

• translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

References

Loading