hemE [Mon Aug 31 2015 13:53:27 GMT+0200 (CEST)]

uroporphyrinogen decarboxylase (uroporphyrinogen III)

locus: BSU10120

pI: 5.26

mw: 39.00 kDa

function: heme biosynthesis

product: uroporphyrinogen decarboxylase (uroporphyrinogen III)

essential: no

ec: 4.1.1.37

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.6|Biosynthesis of heme/ siroheme]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis of cofactors]

The protein

Catalyzed reaction/ biological activity

• Uroporphyrinogen III = coproporphyrinogen + 4 CO₂ (according to Swiss-Prot)

Protein family

• uroporphyrinogen decarboxylase family (according to Swiss-Prot)

Structure

• [PDB|2INF]

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|hemE]-[protein|search|hemH]-[protein|search|hemY]'' [Pubmed|1459957]

References

• 17122346