SubtiBank SubtiBank
hemE
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hemE

uroporphyrinogen decarboxylase (uroporphyrinogen III)
Locus
BSU_10120
Isoelectric point
5.26
Molecular weight
39.49 kDa
Protein length
353 aa Sequence Blast
Gene length
1062 bp Sequence Blast
Function
heme biosynthesis
Product
uroporphyrinogen decarboxylase (uroporphyrinogen III)
Essential
no
E.C.
4.1.1.37
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis of heme/ siroheme

    • Gene

    Coordinates
    1,086,117 1,087,178

    The protein

    Catalyzed reaction/ biological activity

  • 4 H+ + uroporphyrinogen III --> 4 CO2 + coproporphyrinogen III (according to UniProt)

    • Protein family

  • uroporphyrinogen decarboxylase family (single member, according to UniProt)

    • Structure

  • 2INF

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    hemE-hemH-hemY
    Description
    PubMed
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    Biological materials

    Mutant

  • BKE10120 (hemE::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTGATTTCCACCTTTCA, downstream forward: _UP4_TAAGCATATCTTTTGGTATC
  • BKK10120 (hemE::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTGATTTCCACCTTTCA, downstream forward: _UP4_TAAGCATATCTTTTGGTATC

    • References

    Reviews

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    Original Publications

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