similar to quality control membrane serine protease HtrA
product
putative quality control membrane protease
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.1|Protein quality control][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|proteolysis], [SW|sporulation proteins], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigG regulon]Gene
Coordinates on the chromosome (coding sequence)
4,147,567 -> 4,148,769
The protein
Protein family
peptidase S1B family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|HtrA][SW|Localization]
inner spore membrane [Pubmed|26731423][SW|Interactions]
[protein|search|HtrC] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [SW|interactions] [Pubmed|21630458][protein|search|HtrC]-[protein|search|YpeB], for [SW|proteolysis] of [protein|search|YpeB] during [SW|germination] [Pubmed|25384476]Expression and Regulation
Operon
''[protein|search|walR]-[protein|search|walK]-[protein|search|yycH]-[protein|search|yycI]-[protein|search|walJ]-[protein|search|htrC]'' [Pubmed|9829949]''[protein|search|yyxA]'' [Pubmed|9829949][SW|Sigma factor]
for ''[protein|search|htrC]'': [protein|search|SigG] [Pubmed|9829949]Regulation
expressed during vegetative growth, repressed during stationary phase [Pubmed|9829949]''htrC'' transcript expressed during sporulation [Pubmed|9829949]''[protein|search|walR]-[protein|search|walK]-[protein|search|yycH]-[protein|search|yycI]-[protein|search|walJ]-[protein|search|htrC]'' is induced upon deletion of ''[protein|search|htrA]'' and ''[protein|search|htrB]'' [Pubmed|24115457]References
Reviews
Original publications
17600057,12270824,11555295,18957862,10692364,21624103,22307758,22092710,24362423,9829949,21630458,24115457,25384476,26731423 
