SubtiBank SubtiBank
ybbA [Tue Oct 25 2016 17:19:57 GMT+0200 (CEST)]
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ybbA [Tue Oct 25 2016 17:19:57 GMT+0200 (CEST)]

putative bacillibactin esterase
locus
BSU01600
pI
7.00
mw
21.00 kDa
function
iron acquisition from bacillibactin
product
putative bacillibactin esterase
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.3|Acquisition of iron / Other]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.1|Acquisition of iron / Other]
  • [SW|Categories] containing this gene/protein

  • [SW|acquisition of iron], [SW|iron metabolism]
  • This gene is a member of the following [SW|regulons]

  • [SW|Btr regulon], [SW|Fur regulon], [SW|CitB regulon] (putative)
  • Gene

    Coordinates on the chromosome (coding sequence)
    179,595 -> 180,347

    Expression and Regulation

    Operon

  • ''[protein|search|feuA]-[protein|search|feuB]-[protein|search|feuC]-[protein|search|ybbA]'' [Pubmed|12354229]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|17725565]
  • Regulation

  • repressed in the presence of iron ([protein|search|Fur]) [Pubmed|12354229]
  • induced in the presence of iron chelators bacillibactin or enterobactin ([protein|search|Btr]) [Pubmed|17725565]
  • Regulatory mechanism

  • [protein|search|Fur]: transcription repression [Pubmed|12354229]
  • [protein|search|Btr]: transcription activation in the presence of the co-activators bacillibactin or enterobactin [Pubmed|17725565]
  • Additional information

  • the presence of an iron-responsive element bound by [SW|CitB] between ''[SW|feuA]'' and ''[SW|feuB]'' suggests iron-dependent regulation by [SW|CitB] [Pubmed|10468622]
  • References

  • 17725565,12354229,10468622