putative bacillibactin esterase
function
iron acquisition from bacillibactin
product
putative bacillibactin esterase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.3|Acquisition of iron / Other][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.1|Acquisition of iron / Other][SW|Categories] containing this gene/protein
[SW|acquisition of iron], [SW|iron metabolism]This gene is a member of the following [SW|regulons]
[SW|Btr regulon], [SW|Fur regulon], [SW|CitB regulon] (putative)Gene
Coordinates on the chromosome (coding sequence)
179,595 -> 180,347
Expression and Regulation
Operon
''[protein|search|feuA]-[protein|search|feuB]-[protein|search|feuC]-[protein|search|ybbA]'' [Pubmed|12354229][SW|Sigma factor]
[protein|search|SigA] [Pubmed|17725565]Regulation
repressed in the presence of iron ([protein|search|Fur]) [Pubmed|12354229]induced in the presence of iron chelators bacillibactin or enterobactin ([protein|search|Btr]) [Pubmed|17725565]Regulatory mechanism
[protein|search|Fur]: transcription repression [Pubmed|12354229][protein|search|Btr]: transcription activation in the presence of the co-activators bacillibactin or enterobactin [Pubmed|17725565]Additional information
the presence of an iron-responsive element bound by [SW|CitB] between ''[SW|feuA]'' and ''[SW|feuB]'' suggests iron-dependent regulation by [SW|CitB] [Pubmed|10468622]References
17725565,12354229,10468622