ascR [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

alkyl-sulphur catabolism regulator, transcriptional activator of the snaA-tcyJ-tcyK-tcyL-tcyM-tcyN-cmoO-cmoI-cmoJ-ribR-sndA-ytnM operon

locus: BSU29400

pI: 6.23

mw: 35.00 kDa

function: regulation of sulphur metabolism

product: alkyl-sulphur catabolism regulator, transcriptional activator (LysR family)

essential: no

synonyms: ytlI

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.9|Biosynthesis/ acquisition of cysteine]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.4|Sulfur metabolism] → [category|SW 2.6.4.1|Conversion of S-methyl cysteine to cysteine]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis/ acquisition of amino acids], [SW|sulfur metabolism], [SW|transcription factors and their control]

This gene is a member of the following [SW|regulons]

• [SW|CymR regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,008,938 -> 3,009,864

The protein

Protein family

• [SW|LysR family]

Expression and Regulation

Operon

• ''ascR'' [Pubmed|9387221]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|16109943]

Regulation

• repressed in the presence of cysteine ([protein|search|CymR]) [Pubmed|16109943]

Regulatory mechanism

• [protein|search|CymR]: transcription repression [Pubmed|16109943]

References

• 15937167,11390694,16109943,16513748,9387221,16109943,23944997