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dnaX [Fri Jan 29 2016 10:09:34 GMT+0100 (CET)]
DNA polymerase III (gamma and tau subunits) part of the clamp-loader complex and the replisome
product
DNA polymerase III (gamma and tau subunits)
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][SW|Categories] containing this gene/protein
[SW|DNA replication], [SW|essential genes]Gene
Coordinates on the chromosome (coding sequence)
26,814 -> 28,505
Phenotypes of a mutant
essential [Pubmed|12682299]The protein
Catalyzed reaction/ biological activity
Deoxynucleoside triphosphate DNA(n) = diphosphate DNA(n1) (according to Swiss-Prot)required for bacteriophage SPP1 replication [Pubmed|23268446] Structure
[PDB|1JR3][SW|Localization]
forms foci [Pubmed|21958350]Nucleoid (Mid-cell) [Pubmed|16479537][SW|Interactions]
[protein|search|DnaX]-[protein|search|DnaB] [Pubmed|14757052][protein|search|DnaX]-[protein|search|DnaC] [Pubmed|23525462][protein|search|DnaX](3)-[protein|search|HolA]-[protein|search|HolB], the clamp-loader complex [Pubmed|23525462]part of the [SW|replisome]: [protein|search|PolC]-[protein|search|HolA]-[protein|search|HolB]-[protein|search|DnaX]-[protein|search|DnaN]-[protein|search|DnaG]-[protein|search|DnaC]-[protein|search|DnaI]-[protein|search|DnaD]-[protein|search|SsbA]-[protein|search|DnaE]-[protein|search|PriA]-[protein|search|DnaB] [Pubmed|20122408]References
16479537,19415803,14757052,12974630,1703271,12466528,20122408,23525462,23268446,21958350