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dnaX [Fri Jan 29 2016 10:09:34 GMT+0100 (CET)]
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dnaX [Fri Jan 29 2016 10:09:34 GMT+0100 (CET)]

DNA polymerase III (gamma and tau subunits) part of the clamp-loader complex and the replisome
locus
BSU00190
pI
5.00
mw
62.00 kDa
function
DNA replication
product
DNA polymerase III (gamma and tau subunits)
essential
yes
ec
2.7.7.7
synonyms
dnaH, dna-8132

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [SW|Categories] containing this gene/protein

  • [SW|DNA replication], [SW|essential genes]
  • Gene

    Coordinates on the chromosome (coding sequence)
    26,814 -> 28,505

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Catalyzed reaction/ biological activity

  • Deoxynucleoside triphosphate DNA(n) = diphosphate DNA(n1) (according to Swiss-Prot)
  • required for bacteriophage SPP1 replication [Pubmed|23268446]
  • Structure

  • [PDB|1JR3]
  • [SW|Localization]

  • forms foci [Pubmed|21958350]
  • Nucleoid (Mid-cell) [Pubmed|16479537]
  • [SW|Interactions]

  • [protein|search|DnaX]-[protein|search|DnaB] [Pubmed|14757052]
  • [protein|search|DnaX]-[protein|search|DnaC] [Pubmed|23525462]
  • [protein|search|DnaX](3)-[protein|search|HolA]-[protein|search|HolB], the clamp-loader complex [Pubmed|23525462]
  • part of the [SW|replisome]: [protein|search|PolC]-[protein|search|HolA]-[protein|search|HolB]-[protein|search|DnaX]-[protein|search|DnaN]-[protein|search|DnaG]-[protein|search|DnaC]-[protein|search|DnaI]-[protein|search|DnaD]-[protein|search|SsbA]-[protein|search|DnaE]-[protein|search|PriA]-[protein|search|DnaB] [Pubmed|20122408]
  • References

  • 16479537,19415803,14757052,12974630,1703271,12466528,20122408,23525462,23268446,21958350