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cotA [2017-09-06 12:54:07]
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cotA [2017-09-06 12:54:07]

laccase, bilirubin oxidase, spore coat protein (outer)
Locus
BSU06300
Isoelectric point
5.89
Molecular weight
58.33 kDa
Protein length
513 aa Sequence Blast
Gene length
1539 bp Sequence Blast
Function
resistance of the spore
Product
laccase, bilirubin oxidase
Essential
no
E.C.
1.3.3.5
Synonyms
pig
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Lifestyles → Sporulation → Sporulation proteins → Spore coat proteins → Class V
  • Groups of genes → Efp-dependent proteins

    • Gene

    Coordinates
    683,462 → 685,003

    The protein

    Structure

  • 2BHF (reduced form)

    • Localization

  • outer spore coat, more abundant at the mother cell-distal pole of the forespore, localization depends on CotE PubMed

    • Expression and Regulation

    Operons

    Genes
    cotA
    Description
    PubMed

    Sigma factors

  • SigK: sigma factor, PubMed, in SigK regulon

    • Regulatory mechanism

  • GerE: repression, PubMed, in GerE regulon

    • Regulation

  • expressed late during sporulation in the mother cell (SigK, GerE) PubMed

    • Additional information

  • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed
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    Biological materials

    Mutant

  • 1S101 ( cotA::cat), PubMed, available at BGSC
  • 1S134 ( cotA::kan), PubMed, available at BGSC

    • References

    Reviews

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    Original publications

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