transcriptional regulator of anaerobic genes
function
regulation of anaerobiosis, fermentation and overflow metabolism
product
transcription regulator (Crp family)
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.1|Regulators of electron transport][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][SW|Categories] containing this gene/protein
[SW|regulators of electron transport], [SW|transcription factors and their control]This gene is a member of the following [SW|regulons]
[SW|Fnr regulon], [SW|NsrR regulon], [SW|ResD regulon]The protein
Effectors of protein activity
contains an iron-sulfur cluster[SW|Localization]
cytoplasm (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|narK]-[protein|search|fnr]'' [Pubmed|8846791]''[protein|search|fnr]'' [Pubmed|8846791][SW|Sigma factor]
''[protein|search|narK]'': [protein|search|SigA] [Pubmed|8846791]''[protein|search|fnr]'': [protein|search|SigA] [Pubmed|8846791]Regulation
''[protein|search|narK]'': expressed under anaerobic conditions ([protein|search|Fnr]) [Pubmed|8846791,16428414]''[protein|search|fnr]'': expressed under anaerobic conditions ([protein|search|ResD]) [Pubmed|10972836]induced by nitric oxide under anaerobic conditions ([protein|search|NsrR]) [Pubmed|16885456]Regulatory mechanism
[protein|search|ResD]: transcription activation [Pubmed|10972836][protein|search|NsrR]: transcription repression [Pubmed|16885456][protein|search|Fnr]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8846791,16428414 PubMed]References
Reviews
The [SW|Fnr regulon]
Other original publications
8682783,10972836,16885456,8846791,21068385 
