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sbcE [2020-09-29 09:50:58]
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sbcE [2020-09-29 09:50:58]

SMC-like protein, involved in DNA double-strand break repair and competence
locus
BSU_09920
pI
5.79
mw
110.96 kDa
protein length
963 aa Sequence Blast
gene length
2892 bp Sequence Blast
function
DNA double-strand break repair and competence
product
SMC-like protein
essential
no
synonyms
yhaN
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]

    • Gene

    Coordinates
    1,066,077 1,068,968

    The protein

    [SW|Localization]

  • Membrane-proximal (Spotty) [Pubmed|16479537]

    • Expression and Regulation

    Operons

    genes
    [gene|3E27C881BB3DE3FD55B7AD21B8771A859D80786F|yhaO]-[gene|709C4D0AE9C78C9A367F37B9C3B37D2516850D7C|sbcE]-[gene|6D585EB5E56A1E5C1C31680D960043BA08C817E2|yhaM]
    description
    [Pubmed|16267290]

    regulatory mechanism

  • [protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]: repression, [Pubmed|16267290], in [regulon|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA regulon]

    • regulation

  • induced by DNA damage ([protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]) [Pubmed|16267290]
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    Biological materials

    Mutant

  • GP3528 (del spec), available in [SW|Jörg Stülke]'s lab
  • MGNA-A663 (yhaN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/663 NBRP B. subtilis, Japan]
  • BKE09920 ([gene|709C4D0AE9C78C9A367F37B9C3B37D2516850D7C|sbcE]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE09920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TATAATTCGCAAAGCTGTCA, downstream forward: _UP4_TAAAAGAGGTTCTATAGCTG
  • BKK09920 ([gene|709C4D0AE9C78C9A367F37B9C3B37D2516850D7C|sbcE]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK09920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TATAATTCGCAAAGCTGTCA, downstream forward: _UP4_TAAAAGAGGTTCTATAGCTG

    • References

  • 16267290,16479537,19903937,19906728