two-component sensor kinase, regulation of malate uptake
function
regulation of malate uptake
product
two-component sensor kinase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.1|Utilization of organic acids][category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue][SW|Categories] containing this gene/protein
[SW|utilization of specific carbon sources], [SW|protein modification], [SW|transcription factors and their control], [SW|membrane proteins], [SW|phosphoproteins]Gene
Coordinates on the chromosome (coding sequence)
3,237,157 -> 3,238,758
Phenotypes of a mutant
unable to use malate as the single carbon source [Pubmed|12949159]The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of [protein|search|MalR][SW|Domains]
two transmembrane segments[SW|PAS domain]C-terminal histidine phosphotransferase domainModification
autophosphorylation on a His residue[SW|Localization]
cell membrane (according to Swiss-Prot)[SW|Interactions]
[protein|search|MalK]-[protein|search|MalR]Labs working on this gene/protein
[SW|Stephane Aymerich], Microbiology and Molecular Genetics, INRA Paris-Grignon, FranceReferences
10094672,12949160,12949159,12949159,12949160 
