SubtiBank SubtiBank
pdxT [Tue Jul 19 2016 14:50:33 GMT+0200 (CEST)]
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pdxT [Tue Jul 19 2016 14:50:33 GMT+0200 (CEST)]

pyridoxal-5-phosphate synthase (glutaminase domain)
Locus
BSU00120
Isoelectric point
4.00
Molecular weight
21.00 kDa
Function
pyridoxal-5-phosphate biosynthesis
Product
pyridoxal-5-phosphate synthase (glutaminase domain)
Essential
no
E.C.
4.3.3.6
Synonyms
yaaE
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis of pyridoxal phosphate
  • Information processing → Genetics → Newly identified competence genes

    • Categories containing this gene/protein

  • biosynthesis of cofactors, sporulation/ other

    • This gene is a member of the following regulons

  • Spo0A regulon

    • Gene

    Coordinates on the chromosome (coding sequence)
    19,968 -> 20,558

    Phenotypes of a mutant

  • inactivation of pdxT reduces sporulation efficiency to 1.2% that of wild type cells; delayed entry into sporulation PubMed

    • The protein

    Protein family

  • glutamine amidotransferase pdxT/SNO family (according to Swiss-Prot)

    • Structure

  • 2NV2 PdxS-PdxT complex PubMed
  • 2NV0 (PdxT) PubMed

    • Interactions

  • PdxS-PdxT PubMed

    • Expression and Regulation

    Operon

  • pdxS-pdxT PubMed

    • Regulation

  • negatively controlled by Spo0A PubMed
  • repressed under conditions that trigger sporulation (Spo0A) PubMed

    • Regulatory mechanism

  • Spo0A: transcription repression PubMed

    • References

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