SubtiBank SubtiBank
prsA
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

prsA

lipoprotein, post-translocational folding of exported proteins (post-translocation molecular chaperone)
Locus
BSU_09950
Isoelectric point
9.12
Molecular weight
32.36 kDa
Protein length
292 aa Sequence Blast
Gene length
879 bp Sequence Blast
Function
protein folding
Product
post-translocation molecular chaperone
Essential
yes
E.C.
5.2.1.8
Synonyms

Genomic Context

      
Loading

Categories containing this gene/protein

Gene

Coordinates
1,070,364 1,071,242

Phenotypes of a mutant

  • essential PubMed
  • the mutant is viable in the presence of elevated concentrations of Mg2+ PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • catalyses the post-translocational folding of exported proteins PubMed, required for folding of [[penicillin-binding proteins]] (PbpA, PbpB, PbpC, PbpD) PubMed
  • [protein]-peptidylproline (ω=180) --> [protein]-peptidylproline (ω=0) (according to UniProt)
  • Protein family

  • PrsA family (single member, according to UniProt)
  • Domains

  • PpiC domain (aa 134-224) (according to UniProt)
  • Modification

  • PrsA is a lipoprotein with a N-acetyl-S-diacyl-glyceryl-cysteine structure PubMed
  • Structure

    Localization

  • membrane associated (lipoprotein) PubMed
  • distinct spots organized in a helical pattern along the cell membrane PubMed
  • Expression and Regulation

    Operons

    Genes
    Description

    Additional information

  • PrsA is subject to degradation by WprA and other extracellular proteases PubMed
  • view in new tab

    References

    Reviews

    Loading

    Original publications

    Loading