yhaM

RNase, 3 5 exoribonuclease

Locus: BSU_09930

Isoelectric point: 5.85

Molecular weight: 35.53 kDa

Protein length: 314 aa

Gene length: 945 bp

Function: RNA degradation

Product: RNase YhaM

Essential: no

Synonyms

Genomic Context

Loading

Categories containing this gene/protein

• Information processing → RNA synthesis and degradation → RNases → Exoribonucleases

Gene

Coordinates: 1,069,042 1,069,986

The protein

Catalyzed reaction/ biological activity

• 3'-5' exoribonuclease

Protein family

• YhaM family (single member, according to UniProt)

Domains

• HD domain (aa 163-297) (according to UniProt)

Localization

• cytoplasm (Homogeneous) PubMed

Additional information

• subject to Clp-dependent proteolysis upon glucose starvation PubMed

Expression and Regulation

Operons

• Genes: yhaO-sbcE-yhaM
  Description: PubMed

  Regulatory mechanism

  • LexA: repression, PubMed, in LexA regulon

  Regulation

  • induced by DNA damage (LexA) PubMed

Biological materials

Mutant

• MGNA-B499 (yhaM::erm), available at the NBRP B. subtilis, Japan
• BKE09930 (yhaM::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCTATTAAAGCTCCCTC, downstream forward: _UP4_TAACTTAAAAAGGACTGATG
• BKK09930 (yhaM::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTCTATTAAAGCTCCCTC, downstream forward: _UP4_TAACTTAAAAAGGACTGATG

Labs working on this gene/protein

• David Bechhofer, Mount Sinai School, New York, USA Laboratories and Programs/Bechhofer Laboratory?citype=Physician&ciid=Bechhofer David H 1255565 Homepage

References

Reviews

Loading

Original Publications

Loading