SubtiBank SubtiBank
atpE [2019-07-15 08:28:03]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

atpE [2019-07-15 08:28:03]

ATP synthase, part of the Fo complex (subunit c)
locus
BSU_36860
pI
6.43
mw
6.96 kDa
protein length
70 aa Sequence Blast
gene length
213 bp Sequence Blast
function
ATP synthesis
product
ATP synthase (subunit c)
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.5|ATP synthesis] → [category|SW 2.1.5.1|ATPase]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    3,786,620 3,786,832

    The protein

    Catalyzed reaction/ biological activity

  • ATP synthesis [http://www.youtube.com/watch?v=uOoHKCMAUMc see a video]

    • Protein family

  • ATPase C chain family (according to Swiss-Prot)

    • Effectors of protein activity

  • ATPase activity is inhibited upon binding of Mg-ADP to [protein|2A566C2CF8F7B86E05EEF4B7A268E8C102070025|AtpD] [pubmed|30580998]

    • Structure

  • [PDB|1WU0] (from ''Bacillus sp.'', 73% identity)

    • [SW|Localization]

  • membrane [Pubmed|18763711]

    • Expression and Regulation

    Operons

    genes
    [gene|8027AD5C3A92FB9B70E42C119FDEC697A64618C4|atpI]-[gene|CC1894D90AC17487A286B2909964916825055F93|atpB]-[gene|6CF7F6303425D8A51E1E01BF18823139E4259A8F|atpE]-[gene|87311FEA265AD3F5526C78D631E7E51BBF01F0D6|atpF]-[gene|E956A30D97B2941108880F3AD48620C4DB6E0EBD|atpH]-[gene|E3FADE979CE6AB6315F67812608FCE00CF4E2453|atpA]-[gene|492EEC8068043DA770F5DC1D54799C4366AE9A01|atpG]-[gene|2A566C2CF8F7B86E05EEF4B7A268E8C102070025|atpD]-[gene|A9DA64F8C7A60E8E2B1EDC99BEA1BD7DD0135AA6|atpC]
    description
    [Pubmed|9353933]

    regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]

    • regulation

  • [protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • the mRNA is processed between [gene|8027AD5C3A92FB9B70E42C119FDEC697A64618C4|atpI] and [gene|CC1894D90AC17487A286B2909964916825055F93|atpB] by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y], this requires the [protein|EE52DFA35B935E551871D079A9BE877DB2001A3B|YmcA]-[protein|6C9A092F38739A3759793EF8B496569CD02C2E3F|YlbF]-[protein|EBD15C174A03B7FCDFFE4C5DB5D86E93F1B9CAC4|YaaT] complex [Pubmed|29794222]
    • view in new tab

    Biological materials

    Mutant

  • BKE36860 ([gene|6CF7F6303425D8A51E1E01BF18823139E4259A8F|atpE]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE36860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAAAAAGTTCCTCCTTT, downstream forward: _UP4_TAAGCATAAAAGCCTTATAT
  • BKK36860 ([gene|6CF7F6303425D8A51E1E01BF18823139E4259A8F|atpE]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK36860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAAAAAGTTCCTCCTTT, downstream forward: _UP4_TAAGCATAAAAGCCTTATAT

    • References

    Reviews

  • 23356252,23341301,23267178,22822068,21524994,19489730,17208001,16730323

    • Original publications

  • 7961438,18763711,29610201,30580998