atpE

ATP synthase, part of the Fo complex (subunit c)

Locus: BSU_36860

Isoelectric point: 6.43

Molecular weight: 6.96 kDa

Protein length: 70 aa

Gene length: 213 bp

Function: ATP synthesis

Product: ATP synthase (subunit c)

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Metabolism → Electron transport and ATP synthesis → ATP synthesis → ATPase
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,786,620 3,786,832

The protein

Catalyzed reaction/ biological activity

• ATP synthesis see a video

Protein family

• ATPase C chain family (single member, according to UniProt)

Effectors of protein activity

• ATPase activity is inhibited upon binding of Mg-ADP to AtpD PubMed

Structure

• 1WU0 (from Bacillus sp., 73% identity)

Localization

• membrane PubMed

Expression and Regulation

Operons

• Genes: atpI-atpB-atpE-atpF-atpH-atpA-atpG-atpD-atpC
  Description: PubMed

  Regulatory mechanism

  • stringent response: negative regulation, in stringent response

  Regulation

  • RelA dependent downregulation (Class I) during stringent response PubMed
  • the mRNA is processed between atpI and atpB by RNase Y, this requires the YmcA-YlbF-YaaT complex PubMed

Biological materials

Mutant

• BKE36860 (atpE::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGAAAAAGTTCCTCCTTT, downstream forward: _UP4_TAAGCATAAAAGCCTTATAT
• BKK36860 (atpE::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGAAAAAGTTCCTCCTTT, downstream forward: _UP4_TAAGCATAAAAGCCTTATAT

References

Reviews

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Original publications

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