glnM

glutamine ABC transporter (membrane protein)

Locus: BSU_27450

Isoelectric point: 8.42

Molecular weight: 23.55 kDa

Protein length: 216 aa

Gene length: 651 bp

Function: glutamine uptake

Product: glutamine ABC transporter (membrane protein)

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Transporters → ABC transporters → Importers → Uptake of amino acids
• Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation
• Metabolism → Amino acid/ nitrogen metabolism → Utilization of amino acids → Utilization of glutamine/ glutamate
• Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other
• Groups of genes → Membrane proteins

Gene

Coordinates: 2,803,990 2,804,640

The protein

Protein family

• Binding-protein-dependent transport system permease family (according to UniProt)

Paralogous protein(s)

• GlnP

Domains

• ABC transmembrane type-1 domain (aa 17-205) (according to UniProt)

Structure

• 4YMS (complex with GlnP; from Thermoanaerobacter tengcongensis , 40% identity) PubMed

Localization

• cell membrane PubMed

Expression and Regulation

Operons

• Genes: glnQ-glnH-glnM-glnP
  Description: PubMed

  Sigma factors

  • SigE: sigma factor, PubMed, in SigE regulon

  Regulatory mechanism

  • TnrA: activation, PubMed, in TnrA regulon

  Regulation

  • expressed during sporulation (SigE) PubMed

Biological materials

Mutant

• BKE27450 (glnM::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTGCCTATTCACTCCTT, downstream forward: _UP4_AGCTATTGATAAGGAGTGAG
• BKK27450 (glnM::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTGCCTATTCACTCCTT, downstream forward: _UP4_AGCTATTGATAAGGAGTGAG

References

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