ctaO [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

heme O synthase (minor enzyme)

locus: BSU12080

pI: 10.12

mw: 36.00 kDa

function: heme biosynthesis

product: heme O synthase (minor enzyme)

essential: no

synonyms: yjdK

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.6|Biosynthesis of heme/ siroheme]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis of cofactors], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|AbrB regulon]

Gene

Coordinates on the chromosome (coding sequence): 1,279,514 -> 1,280,503

The protein

Protein family

• Protoheme IX farnesyltransferase subfamily (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|CtaB]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|ctaO]'' [Pubmed|21815947]

Regulatory mechanism

• [protein|search|AbrB]: transcription repression [Pubmed|20817675]

Additional information

• the amount of the mRNA is substantially decreased upon depletion of [Rny|search|RNase Y] [PubMed|21815947]

References

• 10675592,20817675,21815947