spoIISB [Mon Jun 20 2016 21:10:46 GMT+0200 (CEST)]

disruption blocks sporulation after septum formation

locus: BSU12820

pI: 10.00

mw: 6.00 kDa

function: sporulation

product: anti-toxin

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.3|Sporulation/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins] → [category|SW 4.3.17.2|Type 2 TA systems]

[SW|Categories] containing this gene/protein

• [SW|sporulation/ other], [SW|toxins, antitoxins and immunity against toxins]

Gene

Coordinates on the chromosome (coding sequence): 1,348,442 -> 1,348,612

Phenotypes of a mutant

• sporulation efficiency is reduced by four orders of magnitude [Pubmed|11371520]

The protein

Structure

• [PDB|3O6Q] (cytoplasmic fragment of [SW|SpoIISA] (CSpoIISA) in complex with [SW|SpoIISB]) [Pubmed|21147767]

[SW|Interactions]

• [SW|SpoIISA]-[SW|SpoIISB] [Pubmed|21147767]

Expression and Regulation

''[SW|spoIISA]-[SW|spoIISB]'' [Pubmed|11371520]

• ''[SW|spoIISB]'' [Pubmed|11371520]

Biological materials

Mutant

• 1S124 ( ''spoIISB''::''tet''), [Pubmed|11371520], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S124&Search=1S124 BGSC]

References

• 18096016,11371520,26300872,21147767