yoxD

similar to 3-oxoacyl- acyl-carrier protein reductase

locus: BSU_18500

pI: 5.33

mw: 25.15 kDa

protein length: 238 aa

gene length: 717 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.8|Phosphorylation on either a Ser, Thr or Tyr residue]
• [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

Gene

Coordinates: 2,018,554 2,019,270

The protein

Protein family

• [SW|Short-chain dehydrogenases/reductases (SDR) family] (according to UniProt)

Paralogous protein(s)

• [protein|B6FF689E65906186F3576B378650D713DB84EDDA|YcdF], [protein|EAEEA4DD9641919830A81185333A2610B964D37C|YhdF], [protein|439B468A13137000FB42E9389391CB4986FFED84|FabG]
• [protein|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036|YhxC]:

Modification

• phosphorylated on ser/ thr/ tyr [Pubmed|16493705]

Structure

• [PDB|2C07] (from Plasmodium Falciparum 37% identity)

Expression and Regulation

Operons

• genes: [gene|6BA346D8A7B496F9618AFAB4FEEF4BD1A41D2C7E|yoxD]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-B094 (yoxD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1093 NBRP B. subtilis, Japan]
• BKE18500 ([gene|6BA346D8A7B496F9618AFAB4FEEF4BD1A41D2C7E|yoxD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18500 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTGAAGCACCCTTTCTT, downstream forward: _UP4_TAAAAATGAAAACCTGTCTT
• BKK18500 ([gene|6BA346D8A7B496F9618AFAB4FEEF4BD1A41D2C7E|yoxD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18500 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTGAAGCACCCTTTCTT, downstream forward: _UP4_TAAAAATGAAAACCTGTCTT

References

• 16493705