yocD

similar to immunity to bacteriotoxins

locus: BSU_19170

pI: 5.58

mw: 36.25 kDa

protein length: 325 aa

gene length: 978 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.18|Toxins, antitoxins and immunity against toxins/ based on similarity]

Gene

Coordinates: 2,088,257 2,089,234

The protein

Protein family

• peptidase S66 family (with [protein|C4F85F85F0C99A59145961E34B19D3AD03D2BC22|YkfA], according to UniProt)

Structure

• [PDB|3SR3] (MccF from ''B. anthracis'', 33% identity, 66% similarity)

Expression and Regulation

Operons

• genes: [gene|CF8F38491E7DBDE77899D47E133B84DBB37C262C|yocC]-[gene|6B36C3B0FA04FBCB20C2C9AEA987DDD211E29629|yocD]
  description: [Pubmed|22383849]

• genes: [gene|6B36C3B0FA04FBCB20C2C9AEA987DDD211E29629|yocD]
  description: [pubmed|22383849]

  regulatory mechanism

  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

Biological materials

Mutant

• MGNA-B413 (yocD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1412 NBRP B. subtilis, Japan]
• BKE19170 ([gene|6B36C3B0FA04FBCB20C2C9AEA987DDD211E29629|yocD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE19170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGAACCCTCCATCAATG, downstream forward: _UP4_TAATCAGCTTGTAAATTTTT
• BKK19170 ([gene|6B36C3B0FA04FBCB20C2C9AEA987DDD211E29629|yocD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK19170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGAACCCTCCATCAATG, downstream forward: _UP4_TAATCAGCTTGTAAATTTTT

References

• 20817675