transcriptional regulator of the extracellular matrix genes, acts in parallel to SinR, AbrB, and DegU
function
control of biofilm formation
product
regulator of the extracellular matrix genes
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation][category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation] → [category|SW 4.1.2.5|Other proteins required for biofilm formation][SW|Categories] containing this gene/protein
[SW|transcription factors and their control], [SW|biofilm formation], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|SigF regulon]The protein
Catalyzed reaction/ biological activity
binds opuAA, tapA, and epsA promoter regions (upstream of the actual promoter) to activate transcription [Pubmed|23646920]binds DNA with high co-operativity due to low conserrvation of binding sites [Pubmed|23646920]Protein family
UPF0296 family (according to Swiss-Prot)Expression and Regulation
[SW|Sigma factor]
[protein|search|SigF] [Pubmed|23396918]Regulation
expressed during vegetative growth and early during sporulation in the forespore ([protein|search|SigF]) [Pubmed|23396918]Labs working on this gene/protein
[SW|Daniel Kearns], Indiana University, Bloomington, USA, [http://www.bio.indiana.edu/facultyresearch/faculty/Kearns.html homepage]References
Reviews
Original publications
19363116,22329926,23123912,23396918,23646920,25035996