checkpoint protein for hag expression, CsrA anatagonist
function
control of CsrA activity
product
flagellar assembly factor, CsrA anatagonist
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.2|Flagellar proteins][SW|Categories] containing this gene/protein
[SW|motility and chemotaxis]This gene is a member of the following [SW|regulons]
[SW|SigD regulon]Gene
Coordinates on the chromosome (coding sequence)
3,636,264 -> 3,636,695
The protein
Catalyzed reaction/ biological activity
[protein|search|FliW] binds [protein|search|CsrA] when [protein|search|Hag] is secreted after hook completion (and [protein|search|FliW] released from the [protein|search|Hag]-[protein|search|FliW] complex) to allow translation of the'' [protein|search|hag]'' mRNA [Pubmed|21895793]Protein family
fliW family (according to Swiss-Prot)Structure
[PDB|5DMD] (from ''Geobacillus thermodenitrificans'') [Pubmed|27551070][PDB|5DMB] ([SW|FliW]-[SW|CsrA] complex) [Pubmed|27551070][SW|Localization]
cytoplasm (according to Swiss-Prot)[SW|Interactions]
[protein|search|FliW]-[protein|search|Hag] [Pubmed|21895793][protein|search|FliW]-[protein|search|CsrA] [Pubmed|21895793,27516547]Additional information
[protein|search|CsrA] and [protein|search|FliW] form a conserved module in many bacteria [Pubmed|21895793,27516547]Expression and Regulation
[SW|Sigma factor]
[SW|SigD] [Pubmed|26577401]References
Reviews
Original Publications
16936039,23144244,21895793,26577401,27516547,27551070