rhaB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

rhamnulokinase

Locus: BSU31200

Isoelectric point: 5.00

Molecular weight: 54.00 kDa

Function: utilization of rhamnose

Product: rhamnulokinase

Essential: no

E.C.: 2.7.1.5

Synonyms: yulC

Genomic Context

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Categories containing this gene/protein

• Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of rhamnose

Categories containing this gene/protein

• utilization of specific carbon sources

This gene is a member of the following regulons

• CcpA regulon, RhaR regulon

Gene

Coordinates on the chromosome (coding sequence): 3,199,565 -> 3,201,022

The protein

Catalyzed reaction/ biological activity

• ATP L-rhamnulose = ADP L-rhamnulose 1-phosphate PubMed

Protein family

• rhamnulokinase family (according to Swiss-Prot)

Structure

• 2UYT (the enzyme of E. coli)

Expression and Regulation

Operon

• rhaEW-rhaR-rhaB-rhaM-rhaA PubMed
• rhaR-rhaB-rhaM-rhaA PubMed

Sigma factor

• SigA PubMed

Regulation

• induced by rhamnose (molecular inducer: rhamnulose-1-phosphate) (RhaR) PubMed
• repressed in the presence of glucose and other preferred carbon sources (CcpA) PubMed

Regulatory mechanism

• RhaR: transcription repression PubMed
• CcpA: transcription repression PubMed

References

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