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rhaB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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rhaB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

rhamnulokinase
locus
BSU31200
pI
5.00
mw
54.00 kDa
function
utilization of rhamnose
product
rhamnulokinase
essential
no
ec
2.7.1.5
synonyms
yulC

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.12|Utilization of rhamnose]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of specific carbon sources]
  • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon], [SW|RhaR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,199,565 -> 3,201,022

    The protein

    Catalyzed reaction/ biological activity

  • ATP L-rhamnulose = ADP L-rhamnulose 1-phosphate [Pubmed|26712933]
  • Protein family

  • rhamnulokinase family (according to Swiss-Prot)
  • Structure

  • [PDB|2UYT] (the enzyme of ''E. coli'')
  • Expression and Regulation

    Operon

  • ''[SW|rhaEW]-[protein|search|rhaR]-[protein|search|rhaB]-[protein|search|rhaM]-[protein|search|rhaA]'' [Pubmed|26712933,22383849]
  • ''[protein|search|rhaR]-[protein|search|rhaB]-[protein|search|rhaM]-[protein|search|rhaA]'' [Pubmed|22383849]
  • [SW|Sigma factor]

  • [SW|SigA] [Pubmed|26712933]
  • Regulation

  • induced by rhamnose (molecular inducer: rhamnulose-1-phosphate) ([SW|RhaR]) [Pubmed|26712933]
  • repressed in the presence of glucose and other preferred carbon sources ([SW|CcpA]) [Pubmed|26712933]
  • Regulatory mechanism

  • [SW|RhaR]: transcription repression [Pubmed|26712933]
  • [SW|CcpA]: transcription repression [Pubmed|26712933]
  • References

  • 26712933,16674975,24391637,22383849