SubtiBank SubtiBank
ywtF [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

ywtF [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

phosphotransferase, attaches teichoic acid, teichuronic acid, or acidic capsular polysaccharide to cell wall peptidoglycan via phosphodiester linkage to N-acteylmuramic acid
locus
BSU35840
pI
9.55
mw
35.00 kDa
function
transfer of anionic cell wall polymers from lipid-linked precursors to peptidoglycan
product
phosphotransferase, responsible for attachment of anionic polymers to peptidoglycan
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.6|Export of anionic polymers and attachment to peptidoglycan]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
  • [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • [SW|Categories] containing this gene/protein

  • [SW|cell wall synthesis], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|membrane proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|SigM regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    3,694,239 -> 3,695,207

    Phenotypes of a mutant

  • a ''[protein|search|tagT]'' mutant has no phenoype, the triple ''[protein|search|tagT] [protein|search|tagU] [protein|search|tagV]'' mutant is unable to grow under normal conditions [Pubmed|21964069]

    • The protein

    Protein family

  • LytR-Cps2a-Psr family [Pubmed|19099556]

    • Paralogous protein(s)

  • [protein|search|TagU], [protein|search|TagV]

    • [SW|Cofactors]

  • Mg(2+) [Pubmed|21964069]

    • Structure

  • [PDB|3MEJ]
  • [PDB|4DE9] [Pubmed|22432711]

    • [SW|Localization]

  • cytoplasmic membrane (with extracytoplasmic catalaytic domain) [Pubmed|21964069]
  • extracellular (signal peptide) [Pubmed|18957862]

    • [SW|Interactions]

  • [protein|search|MreB]-[protein|search|TagT] [Pubmed|21964069]

    • Expression and Regulation

    Operon

  • ''ywtF'' [Pubmed|9353933]

    • [SW|Sigma factor]

  • [protein|search|SigM] [http://www.ncbi.nlm.nih.gov/sites/entrez/18179421 Pubmed]

    • Regulation

  • expressed at high salt concentrations ([protein|search|SigM]) [http://www.ncbi.nlm.nih.gov/sites/entrez/18179421 Pubmed]

    • References

    Reviews

  • 24024634

    • Original publications

  • 18957862,9353933,18179421,19099556,21964069,22432711