yneB

similar to resolvase

locus: BSU_17870

pI: 6.64

mw: 24.59 kDa

protein length: 217 aa

gene length: 654 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.6|DNA repair/ recombination/ based on similarity]

Gene

Coordinates: 1,918,742 1,919,395

Phenotypes of a mutant

• increased sensitivity to DNA-damaging agents [Pubmed|23728628]

The protein

Protein family

• [SW|site-specific recombinase resolvase family] (according to UniProt)

[SW|Domains]

• [SW|Resolvase/invertase-type recombinase catalytic domain] (aa 2-147) (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|7BF591DCDC9635C605D76135481A8A9DB63EE861|yneA]-[gene|67074435B8FDA85C8ED4D8C4ECE3580C4EDFBF2A|yneB]-[gene|5BFD552F8A467C8D95FABE87CC8C5E7F04114886|ynzC]
  description: [Pubmed|12581363]

  regulatory mechanism

  • [protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]: repression, [Pubmed|12581363], in [regulon|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA regulon]

  regulation

  • induced by DNA damage ([protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]) [Pubmed|12581363]

  additional information

  • YneA is rapidly degraded by extracellular proteases ([protein|5ED8301B9681FDD5171A9344A971E891493A6558|CtpA]) [PubMed|29979679,20400548]

Biological materials

Mutant

• BKE17870 ([gene|67074435B8FDA85C8ED4D8C4ECE3580C4EDFBF2A|yneB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE17870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTATCTCTCTTTCCTC, downstream forward: _UP4_TGAATCAGTTGTAAAACTTT
• BKK17870 ([gene|67074435B8FDA85C8ED4D8C4ECE3580C4EDFBF2A|yneB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK17870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTTATCTCTCTTTCCTC, downstream forward: _UP4_TGAATCAGTTGTAAAACTTT

References

• 12581363,16267290,23728628