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uvrC [Mon Aug 31 2015 13:56:07 GMT+0200 (CEST)]
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uvrC [Mon Aug 31 2015 13:56:07 GMT+0200 (CEST)]

excinuclease ABC (subunit C), required for transcription-dependent asymmetry in mutation rates of genes in the two orientations
locus
BSU28490
pI
9.50
mw
69.00 kDa
function
DNA repair after UV damage
product
excinuclease ABC (subunit C)
essential
no
synonyms
uvrB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]
    • syns
    uvrB

    [SW|Categories] containing this gene/protein

  • [SW|DNA repair/ recombination]

    • This gene is a member of the following [SW|regulons]

  • [SW|LexA regulon]

    • The protein

    Protein family

  • uvrC family (according to Swiss-Prot)

    • Structure

  • [PDB|3C65] (5' endonuclease domain, Geobacillus stearothermophilus)

    • [SW|Interactions]

  • [protein|search|UvrB]-[protein|search|UvrC] [Pubmed|16464004]

    • Expression and Regulation

    Operon

  • ''uvrC'' [Pubmed|16267290]

    • Regulation

  • induced upon DNA damage ([protein|search|LexA]) [Pubmed|16267290]

    • Regulatory mechanism

  • [protein|search|LexA]: transcription repression [Pubmed|16267290]]

    • References

    Reviews

  • 16464004,15927210,7801120,22933559

    • Original publications

  • 2174442,2559145,16267290,25713353