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uvrC [2017-8-11 16:0:3]
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uvrC [2017-8-11 16:0:3]

excinuclease ABC (subunit C), required for transcription-dependent asymmetry in mutation rates of genes in the two orientations
locus
BSU28490
pI
9.50
mw
69.28 kDa
protein length
598 aa Sequence Blast
gene length
1794 bp Sequence Blast
function
DNA repair after UV damage
product
excinuclease ABC (subunit C)
essential
no
synonyms
uvrB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]

    • Gene

    Coordinates
    2,911,116 → 2,912,888

    The protein

    Protein family

  • uvrC family (according to Swiss-Prot)

    • Structure

  • [PDB|3C65] (5' endonuclease domain, Geobacillus stearothermophilus)

    • Expression and Regulation

    Operons

    genes
    [gene|6624AA675E9E52FFABFF26055F63471AEF881CC5|uvrC]
    description
    [Pubmed|16267290]

    regulatory mechanism

  • [protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]: repression, [Pubmed|16267290]], in [regulon|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA regulon]

    • regulation

  • induced upon DNA damage ([protein|search|LexA]) [Pubmed|16267290]
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    References

    Reviews

  • 16464004,15927210,7801120,22933559

    • Original publications

  • 2174442,2559145,16267290,25713353