You are currently viewing an outdated version of
SubtiWiki.
Please use
the newest version!
uvrC [2019-07-08 11:35:31]
excinuclease ABC (subunit C), required for transcription-dependent asymmetry in mutation rates of genes in the two orientations
function
DNA repair after UV damage
product
excinuclease ABC (subunit C)
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination][category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]Gene
Coordinates
2,911,116 2,912,888
The protein
Protein family
uvrC family (according to Swiss-Prot)Structure
[PDB|3C65] (5' endonuclease domain, Geobacillus stearothermophilus)Expression and Regulation
Operons
genes
[gene|6624AA675E9E52FFABFF26055F63471AEF881CC5|uvrC]
description
[Pubmed|16267290]
regulatory mechanism
[protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]: repression, [Pubmed|16267290]], in [regulon|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA regulon]regulation
induced upon DNA damage ([protein|search|LexA]) [Pubmed|16267290]view in new tabBiological materials
Mutant
BKE28490 ([gene|6624AA675E9E52FFABFF26055F63471AEF881CC5|uvrC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE28490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGTTACCCTTCCTTAT, downstream forward: _UP4_TAATGTTGTCCTTTTAAATABKK28490 ([gene|6624AA675E9E52FFABFF26055F63471AEF881CC5|uvrC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK28490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGTTACCCTTCCTTAT, downstream forward: _UP4_TAATGTTGTCCTTTTAAATAReferences
Reviews
16464004,15927210,7801120,22933559 Original publications
2174442,2559145,16267290,25713353