trigger enzyme: lichenan-specific phosphotransferase system, EIIB component of the PTS
function
lichenan uptake and phosphorylation,
control of LicR activity
product
trigger enzyme: lichenan-specific
phosphotransferase system, EIIB component
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.2|Phosphotransferase system] → [category|SW 1.2.2.2|Sugar specific PTS proteins][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.27|Utilization of other polymeric carbohydrates][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.4|Control of PRD-type regulators][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.3|Trigger enzyme] → [category|SW 3.4.3.1|Trigger enzymes of the PTS that control the activity of PRD-containing transcription factors][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.3|Phosphorylation on a Cys residue][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue][SW|Categories] containing this gene/protein
[SW|phosphotransferase systems], [SW|utilization of specific carbon sources], [SW|transcription factors and their control], [SW|trigger enzyme], [SW|phosphoproteins], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|LicR regulon]The protein
Catalyzed reaction/ biological activity
Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)Protein family
[SW|PTS] permease, lactose permease (Lac) family [Pubmed|10627040]Modification
phosphorylation on Ser-37 [Pubmed|17218307]Structure
[PDB|1e2b] (from ''E. coli'', 40% identity) [Pubmed|9041631][SW|Localization]
cytoplasm (according to Swiss-Prot)[SW|Interactions]
[protein|search|LicA]-[protein|search|LicB], [protein|search|LicB]-[protein|search|LicC], [protein|search|LicB]-[protein|search|LicR]Expression and Regulation
Operon
''[protein|search|licB]-[protein|search|licC]-[protein|search|licA]-[protein|search|licH]'' [Pubmed|8990303][SW|Sigma factor]
[protein|search|SigA] [Pubmed|8990303]Regulation
carbon catabolite repression ([protein|search|CcpA]) [Pubmed|8990303]induction by oligomeric ß-glucosides ([protein|search|LicR])[Pubmed|8990303]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|8990303][protein|search|LicR]: transcription activation [Pubmed|8990303]References
19087206,8990303,16872404,10438772,10627040,17218307,8990303,9041631 
