dgkA

undecaprenol kinase

locus: BSU_25310

pI: 7.13

mw: 12.40 kDa

protein length: 123 aa

gene length: 372 bp

function: cell wall biosynthesis

product: undecaprenol kinase

essential: no

ec: 2.7.1.107

synonyms: yqxF

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.3|Biosynthesis of lipoteichoic acid]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.2|Biosynthesis of lipoteichoic acid]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 2,611,456 2,611,827

Phenotypes of a mutant

• inactivation of ''[gene|65D3306FE372FF730DD6C62B841AA80CA30AEA43|dgkA]'' reduces sporulation efficiency to 33.7% that of wild type cells [Pubmed|26735940]

The protein

Catalyzed reaction/ biological activity

• ATP + di-trans,octa-cis-undecaprenol --> ADP + di-trans,octa-cis-undecaprenyl phosphate + H⁺ (according to UniProt)

Protein family

• Bacterial diacylglycerol kinase family (single member, according to UniProt)

[SW|Localization]

• cell membrane at the septum [Pubmed|15743965]

Biological materials

Mutant

• BKE25310 ([gene|65D3306FE372FF730DD6C62B841AA80CA30AEA43|dgkA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE25310 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTGAAGAATCGATTCAGCT, downstream forward: _UP4_TAATGGCTGAAAATTCTTAC
• BKK25310 ([gene|65D3306FE372FF730DD6C62B841AA80CA30AEA43|dgkA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK25310 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTGAAGAATCGATTCAGCT, downstream forward: _UP4_TAATGGCTGAAAATTCTTAC

References

• 12923107,17535816,15743965,26735940,29259598