gmuR [2017-8-11 16:0:3]

transcriptional repressor (GntR family) of the gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG operon

Locus: BSU05850

Isoelectric point: 7.44

Molecular weight: 27.23 kDa

Protein length: 237 aa

Gene length: 711 bp

Function: regulation of glucomannan utilization

Product: transcriptional repressor (GntR family)

Essential: no

Synonyms: ydhQ

Genomic Context

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Categories containing this gene/protein

• Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of glucomannan
• Information processing → Regulation of gene expression → Transcription factors and their control → Transcription factors/ other

Gene

Coordinates: 630,170 → 630,883

The protein

Protein family

• GntR family of transcription factors

Structure

• 2WV0 (the structure of NagR, 29% identity) PubMed

Expression and Regulation

Operons

• Genes: gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Regulatory mechanism

  • GmuR: repression, PubMed, in GmuR regulon
  • CcpA: repression, PubMed, in CcpA regulon
  • AbrB: activation, PubMed, in AbrB regulon

  Regulation

  • induced by cellobiose (GmuR) PubMed

Biological materials

Mutant

• MGNA-C192 (ydhQ::erm), available at the NBRP B. subtilis, Japan

References

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