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proG [2017-07-30 17:24:10]
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proG [2017-07-30 17:24:10]

1-pyrroline-5-carboxylate dehydrogenase, the precise role of ProG is unknown
locus
BSU12910
pI
4.91
mw
30.05 kDa
protein length
272 aa Sequence Blast
gene length
816 bp Sequence Blast
function
biosynthesis of proline
product
1-pyrroline-5-carboxylate dehydrogenase
essential
no
ec
1.5.1.2
synonyms
ykeA, yzcA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.2|Biosynthesis/ acquisition of proline]

    • Gene

    Coordinates
    1,359,454 → 1,360,272

    The protein

    Catalyzed reaction/ biological activity

  • L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H (according to Swiss-Prot)

    • Protein family

  • pyrroline-5-carboxylate reductase family (according to Swiss-Prot)

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|63AFCEE5DEA6B2604C02592C5FB52EDFAE68913E|proG]
    description
    [Pubmed|1766370,21784929]
    view in new tab

    Biological materials

    Mutant

  • MGNA-B308 (ykeA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1307 NBRP B. subtilis, Japan]

    • References

    Reviews

  • 25367752

    • Original publications

  • 11418582,1766370,21784929