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alaT [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
similar to PLP-dependent methionine aminotransferase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.15|Biosynthesis/acquisition of L- and D-alanine][SW|Categories] containing this gene/protein
[SW|poorly characterized/ putative enzymes]Gene
Coordinates on the chromosome (coding sequence)
3,225,772 -> 3,226,932
The protein
Structure
[PDB|1DJU] (from ''Pyrococcus horikoshii'', 47% identity) [Pubmed|10671523]Additional information
The gene is annotated in KEGG as an ortholog of N-succinyldiaminopimelate aminotransferase EC 2.6.1.17. It is annotated in Swiss-Prot as “alanine transaminase”. In MetaCyc the gene is marked as “similar to aspartateaminotransferase”. No literature/experimental evidence supporting the annotation is available. [Pubmed|19935659]Expression and Regulation
Operon
''[protein|search|alaR]-[protein|search|alaT]'' [Pubmed|22383849]Additional information
A [protein|search|ncRNA] is predicted between '[protein|search|yugI]' and '[protein|search|alaT]' [PubMed|20525796]References
20525796,22383849,10671523