superoxide dismutase, general stress protein, important for survival of ethanol and paraquat stresses and at low temperatures
function
detoxification of oxygen radicals
product
superoxide dismutase
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.6|Phosphorylation on a Thr residue][SW|Categories] containing this gene/protein
[SW|general stress proteins (controlled by SigB)], [SW|resistance against oxidative and electrophile stress], [SW|membrane proteins], [SW|phosphoproteins], [SW|most abundant proteins]This gene is a member of the following [SW|regulons]
[SW|SigB regulon]Gene
Coordinates on the chromosome (coding sequence)
2,585,434 -> 2,586,042
The protein
Catalyzed reaction/ biological activity
2 superoxide 2 H = O2 H2O2 (according to Swiss-Prot) Protein family
iron/manganese superoxide dismutase family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|SodF]Modification
phosphorylation on Thr-34 AND Thr-70 [Pubmed|17218307][SW|Cofactors]
manganeseStructure
[PDB|2RCV] [Pubmed|18084079][SW|Localization]
cytoplasm [Pubmed|22174384]Expression and Regulation
[SW|Sigma factor]
[protein|search|SigB] [Pubmed|15805528]Regulation
induced by stress ([protein|search|SigB]) [Pubmed|15805528]constitutive expression [Pubmed|22174384]Additional information
belongs to the 100 [SW|most abundant proteins] [PubMed|15378759]References
9393707,9573176,20525796,15805528,17218307,9658017,10074093,22174384,22582280,15378759,18084079