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tagC [2019-02-27 17:51:21]
possibly involved in polyglycerol phosphate teichoic acid biosynthesis
function
biosynthesis of teichoic acid
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.4|Biosynthesis of teichoic acid][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.3|Biosynthesis of teichoic acid]Gene
Coordinates
3,683,438 3,684,766
The protein
Structure
[PDB|5EFV] (from Staphylococcus aureus phage, corresponds to aa 14 ... 286, 32% identity)[SW|Localization]
cytoplasm (homogenous) [Pubmed|16479537]Expression and Regulation
Operons
genes
[gene|60344F56DEB167FA62C16E52E8238393CEE19312|tagC]
description
[Pubmed|7934877]
regulatory mechanism
[protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]: repression, [PubMed|8226626,8969214], in [regulon|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA regulon]regulation
induced upon DNA damage ([protein|search|LexA]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8226626,8969214 PubMed]view in new tabBiological materials
Mutant
BKE35770 ([gene|60344F56DEB167FA62C16E52E8238393CEE19312|tagC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE35770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAATTTACCACCTCTAT, downstream forward: _UP4_TGATAATCAAATAGGCTGTABKK35770 ([gene|60344F56DEB167FA62C16E52E8238393CEE19312|tagC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK35770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAATTTACCACCTCTAT, downstream forward: _UP4_TGATAATCAAATAGGCTGTAReferences
8226626,8969214,9555905,7934877,16267290,16479537