mmgE [2017-05-11 18:37:02]

putative methyl-cis-aconitase

Locus: BSU24130

Isoelectric point: 6.11

Molecular weight: 52.74 kDa

Protein length: 472 aa

Gene length: 1416 bp

Function: mother cell metabolism

Product: unknown

Essential: no

E.C.: 4.2.1.79

Synonyms: yqiP,prpD

Genomic Context

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Categories containing this gene/protein

• Metabolism → Amino acid/ nitrogen metabolism → Utilization of amino acids → Utilization of branched-chain amino acids
• Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other

Gene

Coordinates: 2,508,221 → 2,509,639

The protein

Catalyzed reaction/ biological activity

• (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H₂O (according to Swiss-Prot)

Protein family

• prpD family (according to Swiss-Prot)

Cofactors

• contains an iron-sulfur cluster

Structure

• 1SZQ (60% identity)

Expression and Regulation

Operons

• Genes: mmgA-mmgB-mmgC-mmgD-mmgE-mmgF
  Description: PubMed

  Sigma factors

  • SigE: sigma factor, PubMed, in SigE regulon

  Regulatory mechanism

  • CcpA: repression, PubMed, in CcpA regulon

  Regulation

  • expressed early during sporulation in the mother cell (SigE) PubMed
  • strongly expressed during oligotrophic growth PubMed

References

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