mmgE [Mon Aug 31 2015 13:55:30 GMT+0200 (CEST)]

putative methyl-cis-aconitase

locus: BSU24130

pI: 6.11

mw: 52.00 kDa

function: mother cell metabolism

product: unknown

essential: no

ec: 4.2.1.79

synonyms: yqiP, prpD

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.9|Utilization of branched-chain amino acids]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]

syns: yqiP, prpD

[SW|Categories] containing this gene/protein

• [SW|sporulation proteins], [SW|poorly characterized/ putative enzymes]

This gene is a member of the following [SW|regulons]

• [SW|CcpA regulon], [SW|SigE regulon]

The protein

Catalyzed reaction/ biological activity

• (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H₂O (according to Swiss-Prot)

Protein family

• prpD family (according to Swiss-Prot)

[SW|Cofactors]

• contains an iron-sulfur cluster

Expression and Regulation

Operon

• ''[protein|search|mmgA]-[protein|search|mmgB]-[protein|search|mmgC]-[protein|search|mmgD]-[protein|search|mmgE]-[protein|search|yqiQ]'' [Pubmed|8759838]

[SW|Sigma factor]

• [protein|search|SigE] [Pubmed|15699190,8759838]

Regulation

• expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|15699190,8759838]
• repressed by glucose ([protein|search|CcpA]) [Pubmed|8759838]

Regulatory mechanism

• [protein|search|CcpA]: transcription repression [Pubmed|8759838]

References

• 8759838,15699190