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iolR [2017-12-15 17:11:52]
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iolR [2017-12-15 17:11:52]

transcriptional repressor of the iol operon, DeoR family
Locus
BSU39770
Isoelectric point
6.33
Molecular weight
28.25 kDa
Protein length
251 aa Sequence Blast
Gene length
753 bp Sequence Blast
Function
regulation of myo-inositol catabolism
Product
transcriptional repressor
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of inositol
  • Information processing → Regulation of gene expression → Transcription factors and their control → Transcription factors/ other

    • Gene

    Coordinates
    4,084,799 → 4,085,554

    Phenotypes of a mutant

  • inactivation of iolR reduces sporulation efficiency to 38% that of wild type cells PubMed

    • The protein

    Effectors of protein activity

  • inducer: 2-deoxy-5-keto-D-gluconic acid-6-phosphate

    • Expression and Regulation

    Operons

    Genes
    iolR-iolS
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • IolR: repression, PubMed, in IolR regulon

    • Regulation

  • induced by inositol (IolR) PubMed
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    Biological materials

    Mutant

  • BKE39770 (ΔiolR::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATAAAAAACTCCTTCTT, downstream forward: _UP4_TAACGTTTACAATAGTGTTG
  • BKK39770 (ΔiolR::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATAAAAAACTCCTTCTT, downstream forward: _UP4_TAACGTTTACAATAGTGTTG

    • Labs working on this gene/protein

  • Yasutaro Fujita, University of Fukuyama, Japan
  • [[Ken-ichi Yoshida]], Kobe University, Japan

    • References

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