sigG [Mon Aug 31 2015 13:54:11 GMT+0200 (CEST)]

RNA polymerase sporulation forespore-specific (late) sigma factor SigG

Locus: BSU15330

Isoelectric point: 5.50

Molecular weight: 29.00 kDa

Function: transcription of sporulation genes (late forespore)

Product: RNA polymerase sporulation forespore-specific
(late) sigma factor SigG

Essential: no

Synonyms: spoIIIG

Genomic Context

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Categories containing this gene/protein

• Information processing → RNA synthesis and degradation → Transcription → Sigma factors
• Information processing → Regulation of gene expression → Sigma factors and their control → Sigma factors
• Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other

Syns: spoIIIG

Categories containing this gene/protein

• transcription, sigma factors and their control, sporulation proteins

This gene is a member of the following regulons

• AbrB regulon, SigF regulon, SigG regulon, SinR regulon, Spo0A regulon

The protein

Protein family

• sigma-70 factor family (according to Swiss-Prot)

Paralogous protein(s)

• SigF

Effectors of protein activity

• Gin inhibits SigG activity PubMed
• the activity of SigG-containing RNA polymerase is modulated by YlyA PubMed

Interactions

• SigG-RpoB-RpoC
• CsfB-SigG PubMed
• SpoIIAB-SigG PubMed

Expression and Regulation

Operon

• spoIIGA-sigE-sigG PubMed
• sigG PubMed

Sigma factor

• spoIIGA: SigA PubMed
• sigG: SigF, SigG PubMed

Regulation

• spoIIGA: expressed under conditions that trigger sporulation (Spo0A) PubMed
• sigG: expressed during sporulation (SigF, SigG) PubMed
• the mRNA accumulates in a ymdB mutant PubMed

Regulatory mechanism

• repression by SinR
• Spo0A: transcription activation PubMed
• AbrB: transcription repression PubMed

Labs working on this gene/protein

• Charles Moran, Emory University, NC, USA homepage

References

Reviews

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The SigG regulon

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Original Publications

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